The teams, who stand 16th and 17th respectively and who are separated by just one point were able to produce little that warmed a sparse crowd on a bitterly cold Shropshire night.
Leading goal scorer Clyde Wijnhard netted his 11th goal of the season to give the visitors a 21st minute, but Shrewsbury ultimately secured a share of the spoils when Sagi Burton levelled with a 51st minute penalty.
After being booed off by their fans following a dismal 1-0 home defeat against struggling Torquay last Saturday, Shrewsbury were anxious to make amends and win back the support of the Gay Meadow.
Buoyed by an impressive victory over Carlisle, Macclesfield withstood some early Shrews pressure, before snatching a 21st minute lead, Wijnhard on hand to volley home from six yards after the home defence had failed to clear a Danny Whittaker cross.
But their hopes of securing a second successive win were dashed six minutes into the second half, when centre-half Burton, who made his full Shrewsbury debut on Saturday , converted from the spot after Danny Swailes had handled a Jamie Tolley corner.
Shrewsbury pressed hard for a winner, but chances for Glynn Hurst and Kelvin Langmead were spurned as the Silkmen's rearguard held firm to secure a deserved point.